Washington: Scientists have identified antibodies that can neutralize the new form of the coronavirus, Omicron, and other variants by targeting sites that do not actually change after the virus has changed. . The study has been published in the science journal ‘Nature’ and this research could help in vaccine development and treatment with antibodies that will be effective against not only Omicron but also other emerging variants in the future.
David Wessler, assistant professor at the University of Washington School of Medicine in the US, said, “This study suggests a way to get rid of the continued evolution of the virus by focusing antibodies that target highly conserved sites on the spike protein.” can be taken out.” The omicron form of the coronavirus is unusually characterized by 35 mutations in the spike protein, which the virus uses to enter and infect human cells.
These changes are thought to partly explain why the new forms are able to spread so rapidly, why they infect people who have received a dose of the vaccine, and why they infect those too. Those who have already been infected. Wesler said they were looking for answers to questions related to how these new forms evade the immune system and antibody responses. To assess the impact of these changes, the researchers created an inefficient, non-replicating ‘sudo virus’ and conducted this study with the help of it.
